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DASMIweb tutorial: The basics

Step 3: Initial results

This is the interaction view, the main view of DASMIweb. The top left query panel remained unchanged, while the panel to its left now contains information on the query interactor. The interactions known for BRCA2 are shown in the interaction table below the two boxes. In the example picture, 15 sources have been queried for interactions and they have returned 144 unique interactions. Each source is represented as a column in the table, each interaction partner (or interaction partners, in case of protein complexes) is shown in a table row, and "interaction squares" at the intersections of rows and columns represent interactions. In the example, the fifth interaction between BRCA2 and RAD51A has been reported by 5 sources, as indicated by the 5 interaction squares in the respective table row.

More information on the sources can be found in the header of the interaction table. The small grey number above the name indicates the number of interactions that a source has returned (the number may contain multiple interactions between the same interactors, thus it can be larger than the number of interaction squares in the respective table column. DASMIweb only shows one interaction square for multiple interactions between the same interactors). The background color of the source indicates its type: green represents sources that offer interactions, which have been either experimantally determined or literature curated (e.g. IntAct, MINT, HPRD), yellow sources indicate that the interactions originate from computation predictions (e.g. BIOVERSE, POINT). If you click on the source name, you will be forwarded to either the project website, or if that does not exists, the publication.

Now you might be interested in more information on a particular interaction, for instance, the experimental conditions or additional data on the interaction partner. To request this information, you click on the respective interaction square ... (continue on the next page)


Tutorial step 03